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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LETM1
All Species:
16.36
Human Site:
S118
Identified Species:
30
UniProt:
O95202
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95202
NP_036450.1
739
83354
S118
S
R
P
V
R
D
D
S
V
V
E
K
S
L
K
Chimpanzee
Pan troglodytes
XP_001171298
444
50543
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545925
741
83362
S118
S
P
P
L
R
D
D
S
V
V
E
K
S
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2I0
738
82970
S117
S
S
P
L
G
E
D
S
V
I
E
K
S
L
K
Rat
Rattus norvegicus
Q5XIN6
739
83041
S117
S
S
P
L
G
E
D
S
M
I
E
K
S
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516696
577
64046
I70
A
K
F
L
Q
D
T
I
E
E
M
A
L
K
N
Chicken
Gallus gallus
Q5ZK33
752
85831
S115
S
R
S
L
Q
D
D
S
I
V
E
K
S
L
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LY46
757
86828
K125
G
R
L
L
D
D
S
K
V
E
R
S
L
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91927
1013
113562
K146
T
A
T
A
S
S
E
K
G
Q
N
A
S
A
T
Honey Bee
Apis mellifera
XP_624231
764
87758
A111
T
S
P
K
S
K
V
A
E
K
K
P
P
I
W
Nematode Worm
Caenorhab. elegans
NP_506381
784
88704
L124
A
K
Y
L
W
T
V
L
R
G
A
T
L
S
R
Sea Urchin
Strong. purpuratus
XP_781116
544
61879
Q37
G
S
I
L
T
S
H
Q
D
H
V
F
S
N
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08179
573
64987
K66
D
K
S
K
S
V
T
K
P
V
A
P
T
S
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.2
N.A.
85.8
N.A.
83.9
83.6
N.A.
55
73.5
N.A.
63.5
N.A.
30.3
34.1
35.2
20.4
Protein Similarity:
100
46.9
N.A.
91.3
N.A.
89.1
89
N.A.
62.2
83.9
N.A.
78.7
N.A.
46
56.6
56.6
38.5
P-Site Identity:
100
0
N.A.
86.6
N.A.
66.6
60
N.A.
6.6
73.3
N.A.
20
N.A.
6.6
6.6
0
6.6
P-Site Similarity:
100
0
N.A.
93.3
N.A.
86.6
86.6
N.A.
33.3
93.3
N.A.
26.6
N.A.
20
33.3
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
8
0
0
0
8
0
0
16
16
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
39
39
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
16
8
0
16
16
39
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
16
0
0
0
16
0
0
0
8
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
8
8
16
0
0
0
8
0
% I
% Lys:
0
24
0
16
0
8
0
24
0
8
8
39
0
8
39
% K
% Leu:
0
0
8
62
0
0
0
8
0
0
0
0
24
39
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
8
% N
% Pro:
0
8
39
0
0
0
0
0
8
0
0
16
8
0
0
% P
% Gln:
0
0
0
0
16
0
0
8
0
8
0
0
0
0
0
% Q
% Arg:
0
24
0
0
16
0
0
0
8
0
8
0
0
8
16
% R
% Ser:
39
31
16
0
24
16
8
39
0
0
0
8
54
16
0
% S
% Thr:
16
0
8
0
8
8
16
0
0
0
0
8
8
0
24
% T
% Val:
0
0
0
8
0
8
16
0
31
31
8
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _